Abstract:
Microtubular preparations obtained by different procedures from chick embryonic muscles and brains and from HeLa cells have associated, in addition to the protein kinase which can phosphorylate tubulin, an enzymatic activity which has been identified as that of a diglyceride kinase. They have also consistently associated various phospholipids, lecithin being the principal one. The phosphatidic acid formation is greatly stimulated by exogenous diglycerides or pretreatment with phospholipase C, and it is not present in partially purified preparations of cytoplasmic protein kinases of chick muscle. The significance of these findings is discussed. © 1974.
Registro:
Documento: |
Artículo
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Título: | The presence of phospholipids and diglyceride kinase activity in microtubules from different tissues |
Autor: | Daleo, G.R.; Piras, M.M.; Piras, R. |
Filiación: | Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas, Naturales Universidad de Buenos Aires, Obligado, 2490 Buenos Aires (28), Argentina
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Palabras clave: | diacylglycerol kinase; phospholipid; tubulin; brain; chicken; embryo; hela cell; in vitro study; microtubule; muscle; theoretical study; Alkaline Phosphatase; Animal; Brain Chemistry; Chick Embryo; Diglycerides; Hela Cells; Human; Microtubules; Muscle Proteins; Muscles; Phospholipids; Phosphotransferases; Protein Kinases |
Año: | 1974
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Volumen: | 61
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Número: | 3
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Página de inicio: | 1043
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Página de fin: | 1050
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DOI: |
http://dx.doi.org/10.1016/0006-291X(74)90260-5 |
Título revista: | Biochemical and Biophysical Research Communications
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Título revista abreviado: | Biochem. Biophys. Res. Commun.
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ISSN: | 0006291X
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CODEN: | BBRCA
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CAS: | diacylglycerol kinase, 60382-71-0, 9068-20-6; Alkaline Phosphatase, EC 3.1.3.1; Diglycerides; Muscle Proteins; Phospholipids; Phosphotransferases, EC 2.7; Protein Kinases, EC 2.7.1.37
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v61_n3_p1043_Daleo |
Referencias:
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Citas:
---------- APA ----------
Daleo, G.R., Piras, M.M. & Piras, R.
(1974)
. The presence of phospholipids and diglyceride kinase activity in microtubules from different tissues. Biochemical and Biophysical Research Communications, 61(3), 1043-1050.
http://dx.doi.org/10.1016/0006-291X(74)90260-5---------- CHICAGO ----------
Daleo, G.R., Piras, M.M., Piras, R.
"The presence of phospholipids and diglyceride kinase activity in microtubules from different tissues"
. Biochemical and Biophysical Research Communications 61, no. 3
(1974) : 1043-1050.
http://dx.doi.org/10.1016/0006-291X(74)90260-5---------- MLA ----------
Daleo, G.R., Piras, M.M., Piras, R.
"The presence of phospholipids and diglyceride kinase activity in microtubules from different tissues"
. Biochemical and Biophysical Research Communications, vol. 61, no. 3, 1974, pp. 1043-1050.
http://dx.doi.org/10.1016/0006-291X(74)90260-5---------- VANCOUVER ----------
Daleo, G.R., Piras, M.M., Piras, R. The presence of phospholipids and diglyceride kinase activity in microtubules from different tissues. Biochem. Biophys. Res. Commun. 1974;61(3):1043-1050.
http://dx.doi.org/10.1016/0006-291X(74)90260-5