Registro:

Referencias:

• World malaria report, (2015), World Health Organization Geneva Available from:; Schwartz, L., Brown, G.V., Genton, B., Moorthy, V.S., A review of malaria vaccine clinical projects based on the WHO rainbow table (2012) Malar. J., 11, pp. 11-33
• Young, S.A., Mina, J.G., Denny, P.W., Smith, T.K., Sphingolipid and ceramide homeostasis: potential therapeutic targets (2012) Biochem. Res. Intern., 2012, p. 248135
• Hannun, Y.A., Obeid, L.M., Principles of bioactive lipid signalling: lessons from sphingolipids (2008) Nat. Rev. Mol. Cell Biol., 9, pp. 139-150
• Wang, G., Silva, J., Krishnamurthy, K., Tran, E., Condie, B.G., Bieberich, E., Direct binding to ceramide activates protein kinase C before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells (2005) J. Biol. Chem., 280, pp. 26415-26424
• Huwiler, A., Brunner, J., Hummel, R., Vervoordeldonk, M., Stabel, S., van den Bosch, H., Pfeilschifter, J., Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase (1996) Proc. Natl. Acad. Sci. U. S. A., 93, pp. 6959-6963
• Lee, J.Y., Hannun, Y.A., Obeid, L.M., Ceramide inactivates cellular protein kinase Calpha (1996) J. Biol. Chem., 271, pp. 13169-13174
• van Doorn, R., Nijland, P.G., Dekker, N., Witte, M.E., Lopes-Pinheiro, M.A., van het Hof, B., Kooij, G., de Vries, H.E., Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes (2012) Acta Neuropathol., 124, pp. 397-410
• Lang, P.A., Schenck, M., Nicolay, J.P., Becker, J.U., Kempe, D.S., Lupescu, A., Koka, S., Lang, F., Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide (2007) Nat. Med., 13, pp. 164-170
• Panchal, M., Gaudin, M., Lazar, A.N., Salvati, E., Rivals, I., Ayciriex, S., Dauphinot, L., Duyckaerts, C., Ceramides and sphingomyelinases in senile plaques (2014) Neurobiol. Dis., 65, pp. 193-201
• Wiegmann, K., Schütze, S., Machleidt, T., Witte, D., Krönke, M., Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling (1994) Cell, 78, pp. 1005-1015
• Sanvicens, N., Cotter, T.G., Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells (2006) J. Neurochem., 98, pp. 1432-1444
• Azzouz, N., Rauscher, B., Gerold, P., Cesbron-Delauw, M.F., Dubremetz, J.F., Schwarz, R.T., Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii (2002) Int. J. Parasitol., 32, pp. 677-684
• Gerold, P., Schwarz, R.T., Biosynthesis of glycosphingolipids de-novo by the human malaria parasite Plasmodium falciparum (2001) Mol. Biochem.Parasitol., 112, pp. 29-37
• Ansorge, I., Jeckel, D., Wieland, F., Lingelbach, K., Plasmodium falciparum-infected erythrocytes utilize a synthetic truncated ceramide precursor for synthesis and secretion of truncated sphingomyelin (1995) Biochem. J., 308, pp. 335-341
• Elmendorf, H.G., Haldar, K., Plasmodium falciparum exports the Golgi marker sphingomyelin synthase into a tubovesicular network in the cytoplasm of mature erythrocytes (1994) J. Cell Biol., 124, pp. 449-462
• Haldar, K., Uyetake, L., Ghori, N., Elmendorf, H.G., Li, W.L., The accumulation and metabolism of a fluorescent ceramide derivative in Plasmodium falciparum-infected erythrocytes (1991) Mol. Biochem. Parasitol., 49, pp. 143-156
• Welti, R., Mui, E., Sparks, A., Wernimont, S., Isaac, G., Kirisits, M., Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids (2007) Biochemistry, 46, pp. 13882-13890
• Couto, A.S., Caffaro, C., Uhrig, M.L., Kimura, E., Peres, V.J., Katzin, A.M., Nishioka, M., Erra-Balsells, R., Glycosphingolipids in Plasmodium falciparum. Presence of an active glucosylceramide synthase (2004) Eur. J. Biochem., 271, pp. 2204-2214
• Galati, S., Ekland, E.H., Ruggles, K.V., Chan, R.B., Jayabalasingham, B., Zhou, B., Mantel, P.Y., Fidock, D.A., Profiling the essential nature of lipid metabolism in asexual blood and gametocyte stages of Plasmodium falciparum (2015) Cell Host Microbe, 18 (3), pp. 371-381
• Heung, L.J., Luberto, C., Del Poeta, M., Role of sphingolipids in microbial pathogenesis (2006) Infect. Immun., 74, pp. 28-39
• Taha, T.A., Mullen, T.D., Obeid, L.M., A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death (2006) Biochim. Biophys. Acta, 1758, pp. 2027-2036
• Spiegel, S., Milstien, S., Sphingosine 1-phosphate, a key cell signaling molecule (2002) J. Biol. Chem., 277, pp. 25851-25854
• Kolter, T., Proia, R.L., Sandhoff, K., Combinatorial ganglioside biosynthesis (2002) J. Biol. Chem., 277, pp. 25859-25862
• Kolesnick, R., Altieri, D., Fuks, Z., A CERTain role for ceramide in taxane-induced cell death (2007) Canc. Cell, 11, pp. 473-475
• Bose, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z., Kolesnick, R., Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals (1995) Cell, 82, pp. 405-414
• Rathore, S., Jain, S., Sinha, D., Gupta, M., Asad, M., Srivastava, A., Narayanan, M.S., Mohmmed, A., Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death (2011) Cell Death Dis., 2. , e231
• Kreidenweiss, A., Kremsner, P.G., Mordmuller, B., Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon (2008) Malar. J., 7, pp. 187-195
• Pradel, G., Schlitzer, M., Antibiotics in malaria therapy and their effect on the parasite apicoplast (2010) Curr. Mol. Med., 10, pp. 335-349
• Trager, W., Jensen, J.B., Human malaria parasites in continuous culture (1976) Science, 193, pp. 673-675
• Kimura, E.A., Couto, A.S., Peres, V.J., Casal, O.L., Katzin, A.M., N-linked glycoproteins are related to schizogony of the intraerythrocytic stages in Plasmodium falciparum (1996) J. Biol. Chem., 271, pp. 14452-14461
• Braun-Breton, C., Jendoubi, M., Brunet, E., Perrin, L., Scaife, J., Pereira da Silva, L., In vivo time course of synthesis and processing of major schizont membrane polypeptides in Plasmodium falciparum (1986) Mol. Biochem. Parasitol., 20, pp. 33-43
• Lambros, C., Vanderberg, J.P., Synchronization of erythrocytic stages in culture (1979) J. Parasitol., 65, pp. 418-420
• Miguel, D.C., Yokoyama-Yasunaka, J.K., Andreoli, W.K., Mortara, R.A., Uliana, S.R., Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring L. (Leishmania) amazonensis amastigotes (2007) J. Antimicrob. Chemother., 60, pp. 526-534
• Landoni, M., Duschak, V.G., Peres, V.J., Casal, O.L., Katzin, A.M., Plasmodium falciparum biosynthesizes sulfoglycosphingolipids (2007) Mol. Biochem. Parasitol., 154, pp. 22-29
• Ben Mamoun, C., Prigge, S.T., Vial, H., Targeting the lipid metabolic pathways for the treatment of malaria (2010) Drug Dev. Res., 71 (1), pp. 44-55
• Lauer, S.A., Ghori, N., Haldar, K., Sphingolipid synthesis as a target for chemotherapy against malaria parasites (1995) Proc. Natl. Acad. Sci. U. S. A., 92, pp. 9181-9185
• Hanada, K., Mitamura, T., Fukasawa, M., Magistrado, P.A., Hori, T., Nishijima, M., Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum (2000) Biochem. J., 346, pp. 671-677
• Labaied, M., Dagan, A., Dellinger, M., Gèze, M., Egée, S., Thomas, S.L., Wang, C., Grellier, P., Anti-Plasmodium activity of ceramide analogs (2004) Malar. J., 3, pp. 49-59
• Staines, H.M., Dee, B.C., Shen, M., Clive Ellory, J., (2004) Blood Cell Mol. Dis., 32, pp. 344-348
• Schofield, L., Hewitt, M.C., Evans, K., Siomos, M.A., Seeberger, P.H., Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria (2002) Nature, 418, pp. 785-789
• Debierre-Grockiego, F., Schwarz, R.T., Immunological reactions in response to apicomplexan glycosylphosphatidylinositols (2010) Glycobiology, 20, pp. 801-811
• Thériault, C., Richard, D., Characterization of a putative Plasmodium falciparum SAC1 phosphoinositide-phosphatase homologue potentially required for survival during the asexual erythrocytic stages (2017) Sci. Rep., 7 (1), pp. 12710-12719

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------