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Leloir, L.F.; Olavarría, J.M.; Goldemberg, S.H.; Carminatti, H. "Biosynthesis of glycogen from uridine diphosphate glucose" (1959) Archives of Biochemistry and Biophysics. 81(2):508-520
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Abstract:

An enzyme which leads to the formation of glycogen according to the equation: UDPG + primer → UDP + glucosyl α (1 → 4) primer has been studied. The optimal conditions for activity were determined with a partially purified preparation from rat muscle. The reaction requires the presence of a polysaccharide as primer and is strongly activated by hexose 6-phosphates. Using UDPG labeled in the glucose moiety, it was found that the radioactivity was transferred to the glycogen from which it could be removed as maltose with β-amylase or as G-1-P with phosphorylase. Thus it seems that the glucose residue becomes linked α (1 → 4) to the polysaccharide. Several inhibitors were tested as well as the occurrence of the enzyme in different organs. © 1959.

Registro:

Documento: Artículo
Título:Biosynthesis of glycogen from uridine diphosphate glucose
Autor:Leloir, L.F.; Olavarría, J.M.; Goldemberg, S.H.; Carminatti, H.
Filiación:Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, ôbligado 2490 Buenos Aires, Argentina
Palabras clave:glycogen; nucleoside; nucleotide; article; GLYCOGEN/metabolism; metabolism; muscle; MUSCLES/metabolism; NUCLEOSIDES AND NUCLEOTIDES/metabolism; GLYCOGEN/metabolism; MUSCLES/metabolism; NUCLEOSIDES AND NUCLEOTIDES/metabolism; Glycogen; Muscles; Nucleosides; Nucleotides
Año:1959
Volumen:81
Número:2
Página de inicio:508
Página de fin:520
DOI: http://dx.doi.org/10.1016/0003-9861(59)90232-2
Título revista:Archives of Biochemistry and Biophysics
Título revista abreviado:Arch. Biochem. Biophys.
ISSN:00039861
CODEN:ABBIA
CAS:glycogen, 9005-79-2; Glycogen, 9005-79-2; Nucleosides; Nucleotides
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00039861_v81_n2_p508_Leloir

Citas:

---------- APA ----------
Leloir, L.F., Olavarría, J.M., Goldemberg, S.H. & Carminatti, H. (1959) . Biosynthesis of glycogen from uridine diphosphate glucose. Archives of Biochemistry and Biophysics, 81(2), 508-520.
http://dx.doi.org/10.1016/0003-9861(59)90232-2
---------- CHICAGO ----------
Leloir, L.F., Olavarría, J.M., Goldemberg, S.H., Carminatti, H. "Biosynthesis of glycogen from uridine diphosphate glucose" . Archives of Biochemistry and Biophysics 81, no. 2 (1959) : 508-520.
http://dx.doi.org/10.1016/0003-9861(59)90232-2
---------- MLA ----------
Leloir, L.F., Olavarría, J.M., Goldemberg, S.H., Carminatti, H. "Biosynthesis of glycogen from uridine diphosphate glucose" . Archives of Biochemistry and Biophysics, vol. 81, no. 2, 1959, pp. 508-520.
http://dx.doi.org/10.1016/0003-9861(59)90232-2
---------- VANCOUVER ----------
Leloir, L.F., Olavarría, J.M., Goldemberg, S.H., Carminatti, H. Biosynthesis of glycogen from uridine diphosphate glucose. Arch. Biochem. Biophys. 1959;81(2):508-520.
http://dx.doi.org/10.1016/0003-9861(59)90232-2