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Abstract:

We describe the synthesis and characterization of a ruthenium-bipyridyl complex bearing a rhodamine-based fluorescent ligand. The complex is weakly fluorescent due to the quenching of rhodamine. Upon irradiation of the MLCT band it releases rhodamine in a fast and clean heterolytic reaction, increasing its fluorescence nearly 6-fold and making it the first visible-light activatable fluorophore based in transition metal chemistry. These properties and its lack of toxicity make it a good candidate for its use as a biologically friendly caged fluorescent probe. The use of this probe as a neuronal marker, and as a flow profiler in a thin, planar cavity and in a model flow injection analysis (FIA) is demonstrated. © 2010 American Chemical Society.

Registro:

Documento: Artículo
Título:A ruthenium-rhodamine complex as an activatable fluorescent probe
Autor:Del Marmol, J.; Filevich, O.; Etchenique, R.
Filiación:Departamento de Química Inorgánica, Analítica Y Química Física, Universidad de Buenos Aires, Ciudad Universitaria Pabellón 2, AR1428EHA Buenos Aires, Argentina
Palabras clave:Flow-injection analysis; Fluorescent probes; Neuronal markers; Planar cavities; Synthesis and characterizations; Transition metal chemistry; Visible light; Chelation; Fluorescence; Fluorophores; Ruthenium; Synthesis (chemical); Ruthenium compounds
Año:2010
Volumen:82
Número:14
Página de inicio:6259
Página de fin:6264
DOI: http://dx.doi.org/10.1021/ac1012128
Título revista:Analytical Chemistry
Título revista abreviado:Anal. Chem.
ISSN:00032700
CODEN:ANCHA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00032700_v82_n14_p6259_DelMarmol

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Citas:

---------- APA ----------
Del Marmol, J., Filevich, O. & Etchenique, R. (2010) . A ruthenium-rhodamine complex as an activatable fluorescent probe. Analytical Chemistry, 82(14), 6259-6264.
http://dx.doi.org/10.1021/ac1012128
---------- CHICAGO ----------
Del Marmol, J., Filevich, O., Etchenique, R. "A ruthenium-rhodamine complex as an activatable fluorescent probe" . Analytical Chemistry 82, no. 14 (2010) : 6259-6264.
http://dx.doi.org/10.1021/ac1012128
---------- MLA ----------
Del Marmol, J., Filevich, O., Etchenique, R. "A ruthenium-rhodamine complex as an activatable fluorescent probe" . Analytical Chemistry, vol. 82, no. 14, 2010, pp. 6259-6264.
http://dx.doi.org/10.1021/ac1012128
---------- VANCOUVER ----------
Del Marmol, J., Filevich, O., Etchenique, R. A ruthenium-rhodamine complex as an activatable fluorescent probe. Anal. Chem. 2010;82(14):6259-6264.
http://dx.doi.org/10.1021/ac1012128