Artículo

Burgos, J.M.; Begher, S.; Silva, H.M.V.; Bisio, M.; Duffy, T.; Levin, M.J.; Macedo, A.M.; Schijman, A.G. "Case report: Molecular identification of Trypanosoma cruzi i tropism for central nervous system in chagas reactivation due to AIDS" (2008) American Journal of Tropical Medicine and Hygiene. 78(2):294-297
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Abstract:

Trypanosoma cruzi lineages, microsatellite allelic polymorphism, and mithocondrial gene haplotypes were directly typified from peripheral blood and cerebrospinal fluid specimens of a Bolivian patient with Chagas disease with accompanying AIDS and central nervous system severe involvement. Of note, the patient's blood was infected by a mixture of T. cruzi I and T. cruzi IId/e polyclonal populations while the cerebrospinal fluid showed only a monoclonal T. cruzi I population. Our findings do not corroborate the original assumption of innocuity for T. cruzi I in the southern cone of the Americas and highlight lineage I tropism for central nervous system causing lethal Chagas reactivation. Copyright © 2008 by The American Society of Tropical Medicine and Hygiene.

Registro:

Documento: Artículo
Título:Case report: Molecular identification of Trypanosoma cruzi i tropism for central nervous system in chagas reactivation due to AIDS
Autor:Burgos, J.M.; Begher, S.; Silva, H.M.V.; Bisio, M.; Duffy, T.; Levin, M.J.; Macedo, A.M.; Schijman, A.G.
Filiación:Laboratorio de Biología Molecular de la Enfermedad de Chagas, INGEBI-CONICET, Vuelta de Obligado 2490, Buenos Aires 1428, Argentina
Hospital Pirovamo, Monroe 3555, Capital Federal, Argentina
Universidade Federal de Mina Gerais, Av Antonio Carlos 6627, Belo Horizonte, HG, Brazil
Palabras clave:parasite antibody; cytochrome c oxidase; microsatellite DNA; protozoal DNA; acquired immune deficiency syndrome; adult; allele; article; blood sampling; case report; central nervous system; cerebrospinal fluid; Chagas disease; genetic polymorphism; haplotype; human; male; microsatellite marker; mitochondrion; nonhuman; parasite identification; Trypanosoma cruzi; acquired immune deficiency syndrome; AIDS related complex; animal; blood; Bolivia; central nervous system; central nervous system infection; Chagas disease; fatality; genetics; isolation and purification; parasitology; physiology; plant growth; recurrent disease; restriction fragment length polymorphism; Trypanosoma cruzi; Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Animals; Bolivia; Central Nervous System; Central Nervous System Protozoal Infections; Chagas Disease; DNA, Protozoan; Electron Transport Complex IV; Fatal Outcome; Humans; Male; Microsatellite Repeats; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Recurrence; Tropism; Trypanosoma cruzi
Año:2008
Volumen:78
Número:2
Página de inicio:294
Página de fin:297
Título revista:American Journal of Tropical Medicine and Hygiene
Título revista abreviado:Am. J. Trop. Med. Hyg.
ISSN:00029637
CODEN:AJTHA
CAS:cytochrome c oxidase, 72841-18-0, 9001-16-5; DNA, Protozoan; Electron Transport Complex IV, EC 1.9.3.1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00029637_v78_n2_p294_Burgos

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Citas:

---------- APA ----------
Burgos, J.M., Begher, S., Silva, H.M.V., Bisio, M., Duffy, T., Levin, M.J., Macedo, A.M.,..., Schijman, A.G. (2008) . Case report: Molecular identification of Trypanosoma cruzi i tropism for central nervous system in chagas reactivation due to AIDS. American Journal of Tropical Medicine and Hygiene, 78(2), 294-297.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00029637_v78_n2_p294_Burgos [ ]
---------- CHICAGO ----------
Burgos, J.M., Begher, S., Silva, H.M.V., Bisio, M., Duffy, T., Levin, M.J., et al. "Case report: Molecular identification of Trypanosoma cruzi i tropism for central nervous system in chagas reactivation due to AIDS" . American Journal of Tropical Medicine and Hygiene 78, no. 2 (2008) : 294-297.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00029637_v78_n2_p294_Burgos [ ]
---------- MLA ----------
Burgos, J.M., Begher, S., Silva, H.M.V., Bisio, M., Duffy, T., Levin, M.J., et al. "Case report: Molecular identification of Trypanosoma cruzi i tropism for central nervous system in chagas reactivation due to AIDS" . American Journal of Tropical Medicine and Hygiene, vol. 78, no. 2, 2008, pp. 294-297.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00029637_v78_n2_p294_Burgos [ ]
---------- VANCOUVER ----------
Burgos, J.M., Begher, S., Silva, H.M.V., Bisio, M., Duffy, T., Levin, M.J., et al. Case report: Molecular identification of Trypanosoma cruzi i tropism for central nervous system in chagas reactivation due to AIDS. Am. J. Trop. Med. Hyg. 2008;78(2):294-297.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00029637_v78_n2_p294_Burgos [ ]