Abstract:
Background: Renal artery stenosis (RAS) is a potentially reversible cause of hypertension and renal insufficiency and is associated with poor prognosis. Methods: We aimed to identify simple predictors of significant RAS among patients undergoing coronary angiography. Prospective data were collected on 843 consecutive patients who underwent cardiac catheterization and abdominal aortography. Stenoses ≥75% were considered significant. Multivariable logistic regression was used to assess the relationship between baseline characteristics and coronary anatomy with significant RAS. A simple risk score was derived from the model. Results: The prevalence of RAS ≥75% was 11.7%. Independent predictors of significant RAS were older age, higher creatinine levels, peripheral vascular disease, number of cardiovascular drugs, hypertension, female sex, and 3-vessel coronary artery disease or previous coronary artery bypass graft. The concordance index of the model was 0.802. These variables were used to develop a simple predictive score of significant RAS for patients undergoing cardiac catheterization. The prevalence of RAS increased stepwise with increasing score values: 0.6% for a score ≤5, 1.5% for 6 to 7, 6.1% for 8 to 9, 12.2% for 10 to 11, 18.7% for 12 to 14, 35.7% for 15 to 17, and 62.1% for ≥18 (P < .001). Approximately one third of the patients had a score ≥11, which yielded a sensitivity of 76% and a specificity of 71%. Conclusions: Renal artery stenosis is a relatively common finding among patients referred for coronary angiography. A simple score can predict the presence of significant RAS among patients referred for cardiac catheterization. © 2005, Mosby, Inc. All rights reserved.
Registro:
Documento: |
Artículo
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Título: | A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization |
Autor: | Cohen, M.G.; Andrés Pascua, J.; Garcia-Ben, M.; Rojas-Matas, C.A.; Gabay, J.M.; Berrocal, D.H.; Tan, W.A.; Stouffer, G.A.; Montoya, M.; Fernandez, A.D.; Halac, M.E.; Grinfeld, L.R. |
Filiación: | Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States Servicio de Hemodinamia Y Cardiología Intervencionista, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina Division of Cardiology, University of North Carolina at Chapel Hill, Bioinformatics Building, 130 Mason Farm Road, CB # 7075, Chapel Hill, NC 27599-7075, United States
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Palabras clave: | creatinine; abdominal angiography; adult; aged; angiocardiography; aortography; article; controlled study; coronary artery bypass graft; coronary artery disease; diagnostic accuracy; female; heart catheterization; human; hypertension; kidney artery stenosis; major clinical study; male; multivariate analysis; peripheral vascular disease; prediction; prevalence; priority journal; prospective study; scoring system; Adult; Aged; Argentina; Blood Pressure; Cholesterol; Coronary Angiography; Coronary Disease; Female; Germany; Heart Catheterization; Humans; Male; Middle Aged; Multivariate Analysis; Peripheral Vascular Diseases; Regression Analysis; Renal Artery Obstruction |
Año: | 2005
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Volumen: | 150
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Número: | 6
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Página de inicio: | 1204
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Página de fin: | 1211
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DOI: |
http://dx.doi.org/10.1016/j.ahj.2005.02.019 |
Título revista: | American Heart Journal
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Título revista abreviado: | Am. Heart J.
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ISSN: | 00028703
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CODEN: | AHJOA
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CAS: | creatinine, 19230-81-0, 60-27-5; Cholesterol, 57-88-5
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00028703_v150_n6_p1204_Cohen |
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Citas:
---------- APA ----------
Cohen, M.G., Andrés Pascua, J., Garcia-Ben, M., Rojas-Matas, C.A., Gabay, J.M., Berrocal, D.H., Tan, W.A.,..., Grinfeld, L.R.
(2005)
. A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization. American Heart Journal, 150(6), 1204-1211.
http://dx.doi.org/10.1016/j.ahj.2005.02.019---------- CHICAGO ----------
Cohen, M.G., Andrés Pascua, J., Garcia-Ben, M., Rojas-Matas, C.A., Gabay, J.M., Berrocal, D.H., et al.
"A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization"
. American Heart Journal 150, no. 6
(2005) : 1204-1211.
http://dx.doi.org/10.1016/j.ahj.2005.02.019---------- MLA ----------
Cohen, M.G., Andrés Pascua, J., Garcia-Ben, M., Rojas-Matas, C.A., Gabay, J.M., Berrocal, D.H., et al.
"A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization"
. American Heart Journal, vol. 150, no. 6, 2005, pp. 1204-1211.
http://dx.doi.org/10.1016/j.ahj.2005.02.019---------- VANCOUVER ----------
Cohen, M.G., Andrés Pascua, J., Garcia-Ben, M., Rojas-Matas, C.A., Gabay, J.M., Berrocal, D.H., et al. A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization. Am. Heart J. 2005;150(6):1204-1211.
http://dx.doi.org/10.1016/j.ahj.2005.02.019