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Abstract:

In the holometabolous insect Drosophila melanogaster, genetic, physiological and anatomical aspects of olfaction are well known in the adult stage, while larval stages olfactory behavior has received some attention it has been less studied than its adult counterpart. Most of these studies focus on olfactory receptor (Or) genes that produce peripheral odor recognition. In this paper, through a loss-of-function screen using P-element inserted lines and also by means of expression analyses of larval olfaction candidate genes, we extended the uncovering of the genetic underpinnings of D. melanogaster larval olfactory behavior by demonstrating that larval olfactory behavior is, in addition to Or genes, orchestrated by numerous genes with diverse functions. Also, our results point out that the genetic architecture of olfactory behavior in D. melanogaster presents a dynamic and changing organization across environments and ontogeny. © 2013 Springer Science+Business Media New York.

Registro:

Documento: Artículo
Título:Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development
Autor:Lavagnino, N.J.; Arya, G.H.; Korovaichuk, A.; Fanara, J.J.
Filiación:Departamento de Ecología, Genética y Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina
Instituto de Ecología, Genética y Evolución (IEGEBA), CONICET, Buenos Aires, Argentina
Department of Systems Neuroscience, Cajal Institute, Consejo Superior de Investigaciones Científicas, 28002 Madrid, Spain
Department of Biology, North Carolina State University, Raleigh NC 27695, United States
W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh NC 27695, United States
Palabras clave:Development; Drosophila melanogaster; Genetic architecture; Olfactory behavior; article; controlled study; Drosophila melanogaster; dynamics; female; gene; gene expression; gene function; gene insertion; gene rearrangement; genetic analysis; genetic organization; genetic similarity; genetic underpinning; genetic variability; heredity; larval stage; nonhuman; olfactory system; ontogeny; OR gene; smelling; animal; gene; gene expression profiling; gene expression regulation; genetics; homozygote; larva; mutagenesis; nucleotide sequence; odor; olfactory receptor; physiology; time; Drosophila melanogaster; Hexapoda; Animals; DNA Mutational Analysis; Drosophila melanogaster; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, Insect; Homozygote; Larva; Mutagenesis; Olfactory Receptor Neurons; Smell; Time Factors
Año:2013
Volumen:43
Número:4
Página de inicio:348
Página de fin:359
DOI: http://dx.doi.org/10.1007/s10519-013-9592-z
Título revista:Behavior Genetics
Título revista abreviado:Behav. Genet.
ISSN:00018244
CODEN:BHGNA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00018244_v43_n4_p348_Lavagnino

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Citas:

---------- APA ----------
Lavagnino, N.J., Arya, G.H., Korovaichuk, A. & Fanara, J.J. (2013) . Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development. Behavior Genetics, 43(4), 348-359.
http://dx.doi.org/10.1007/s10519-013-9592-z
---------- CHICAGO ----------
Lavagnino, N.J., Arya, G.H., Korovaichuk, A., Fanara, J.J. "Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development" . Behavior Genetics 43, no. 4 (2013) : 348-359.
http://dx.doi.org/10.1007/s10519-013-9592-z
---------- MLA ----------
Lavagnino, N.J., Arya, G.H., Korovaichuk, A., Fanara, J.J. "Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development" . Behavior Genetics, vol. 43, no. 4, 2013, pp. 348-359.
http://dx.doi.org/10.1007/s10519-013-9592-z
---------- VANCOUVER ----------
Lavagnino, N.J., Arya, G.H., Korovaichuk, A., Fanara, J.J. Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development. Behav. Genet. 2013;43(4):348-359.
http://dx.doi.org/10.1007/s10519-013-9592-z