Artículo
Abstract:
The possible influence of qualitative dietary changes on carbohydrate tolerance and plasma lipid levels of non insulin-dependent diabetics was studied in 5 maturity-onset diabetics of normal weight who remained stabilized with 5 to 10 mg glibenclamide. Each patient was submitted to 4 isocaloric qualitatively different diets: standard, high carbohydrate, high fat, and high protein. Each diet was administered for 30 consecutive days in random order. Apart from assessing metabolic control, an oral glucose tolerance test (40 g/m2 body surface area) was performed in the morning, at the end of each period. Blood was collected at 0, 60, 120, and 180 min after starting glucose ingestion, for blood glucose and plasma FFA determinations. Fasting total lipids, triglycerides, lipoalbumins, and α- and β-lipoproteins, and 24-h urinary urea were also investigated. The findings did not disclose any differences in carbohydrate tolerance after the various diets. The drop in FFA levels following an oral glucose load was greatest after the high protein diet. Fasting total lipids were lowest after the high fat and high protein diets. Triglycerides fell after the high fat diet. The remaining parameters showed less significant variations. Although no differences were observed in carbohydrate tolerance, the conclusion is that relative carbohydrate restriction together with sufficient protein supply might be most beneficial for non insulin-dependent diabetics. © 1974 The Publishing House «IL PONTE».
Registro:
| Documento: | Artículo |
| Título: | Effects of diet composition on glucose tolerance and plasma lipids of non insulin-dependent diabetics |
| Autor: | Senderey, S.; Brandi, P.; Aparicio, N.J.; Fishberg, D. |
| Filiación: | Cátedra De Nutrición, Pabellón Francisco T. Olivera Hospital Rawson, Buenos Aires, Argentina |
| Palabras clave: | Glibenclamide; Glucose tolerance; Influence of diet; Plasma lipids; Stable maturityonset diabetes; fat; fatty acid; glibenclamide; insulin; lipoprotein; low density lipoprotein; protein; triacylglycerol; carbohydrate tolerance; clinical trial; controlled study; diabetes mellitus; diet; fatty acid blood level; glucose blood level; glucose tolerance test; human; lipid blood level; major clinical study; oral drug administration; randomized controlled trial; theoretical study; urea urine level; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Fasting; Fatty Acids, Nonesterified; Glucose Tolerance Test; Human; Lipids; Lipoproteins; Male; Middle Age; Triglycerides |
| Año: | 1974 |
| Volumen: | 11 |
| Número: | 6 |
| Página de inicio: | 468 |
| Página de fin: | 478 |
| DOI: | http://dx.doi.org/10.1007/BF02624586 |
| Título revista: | Acta diabetologia latina |
| Título revista abreviado: | Acta diabet. lat |
| ISSN: | 00015563 |
| CODEN: | ADILA |
| CAS: | glibenclamide, 10238-21-8; insulin, 9004-10-8; protein, 67254-75-5; Blood Glucose; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Fatty Acids, Nonesterified; Lipids; Lipoproteins; Triglycerides |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00015563_v11_n6_p468_Senderey |
Referencias:
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Citas:
---------- APA ----------
Senderey, S., Brandi, P., Aparicio, N.J. & Fishberg, D. (1974) . Effects of diet composition on glucose tolerance and plasma lipids of non insulin-dependent diabetics. Acta diabetologia latina, 11(6), 468-478.http://dx.doi.org/10.1007/BF02624586
---------- CHICAGO ----------
Senderey, S., Brandi, P., Aparicio, N.J., Fishberg, D. "Effects of diet composition on glucose tolerance and plasma lipids of non insulin-dependent diabetics" . Acta diabetologia latina 11, no. 6 (1974) : 468-478.http://dx.doi.org/10.1007/BF02624586
---------- MLA ----------
Senderey, S., Brandi, P., Aparicio, N.J., Fishberg, D. "Effects of diet composition on glucose tolerance and plasma lipids of non insulin-dependent diabetics" . Acta diabetologia latina, vol. 11, no. 6, 1974, pp. 468-478.http://dx.doi.org/10.1007/BF02624586
---------- VANCOUVER ----------
Senderey, S., Brandi, P., Aparicio, N.J., Fishberg, D. Effects of diet composition on glucose tolerance and plasma lipids of non insulin-dependent diabetics. Acta diabet. lat. 1974;11(6):468-478.http://dx.doi.org/10.1007/BF02624586
