Registro:

Referencias:

• Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., (2001) Molecular biology of the cell, , Garland Science
• Angeli, D., Ferrell, J.E., Sontag, E.D., Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems (2004) Proc Natl Acad Sci USA, 101, p. 1822
• Bluthgen, N., Bruggeman, F.J., Legewie, S., Herzel, H., Westerhoff, H.V., Kholodenko, B.N., Detection of multi-stability, bifurcations, and hysteresis in a large class of biological positive-feedback systems (2006) FEBS J, 273, p. 895
• Del Vecchio, D., Ninfa, A.J., Sontag, E.D., Modular cell biology: retroactivity and insulation (2008) Mol Syst Biol, 4, p. 161
• Fages, F., Soliman, S., (2008) Lecture notes in computer science, 5054. , Springer, Berlin
• Feliu, E., Wiuf, C., Enzyme sharing as a cause of multi-stationarity in signaling systems (2012) J R Soc Interface, 9 (71), pp. 1224-1232
• Goldbeter, A., Koshland, J., An amplified sensitivity arising from covalent modification in biological systems (1981) Proc Natl Acad Sci USA, 78 (11), pp. 6840-6844. , DE
• Gonze, D., Goldbeter, A., A model for a network of phosphorylation-dephosphorylation cycles displaying the dynamics of dominoes and clocks (2001) J Theor Biol, 210, p. 167
• Gouzé, J., Positive and negative circuits in dynamical systems (1998) J Biol Syst, 6 (1), p. 11
• Gross, T., Feudel, U., Generalized models as an universal approach to the analysis of nonlinear dynamical systems (2006) Phys Rev E, 73, pp. 016205-016214
• Huang, C.Y., Ferrell, J., Ultrasensitivity in themitogen-activated protein kinase cascade (1996) Proc Natl Acad Sci USA, 93 (19), pp. 10078-10083. , JE
• Jiang, P., Ventura, A.C., Sontag, E.D., Merajver, S.D., Ninfa, A.J., Del Vecchio, D., Load-induced modulation of signal transduction networks (2011) Sci Signal, 4 (194), pp. 1-10
• Kholodenko, B., Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades (2000) Eur J Biochem, 267, p. 1583
• Kim, Y., Paroush, Z., Nairz, K., Hafen, E., Jimenez, G., Shvartsman, S.Y., Substrate-dependent control of mapk phosphorylation in vivo (2011) Mol Syst Biol, 7, p. 467
• Markevich, N.I., Hoek, J.B., Kholodenko, B.N., Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades (2004) J Cell Biol, 164, p. 353
• Murray, J., (2002) Mathematical Biology I: An Introduction, , 3rd edn., Berlin: Springer
• Murray, A.W., Kirschner, M.W., Dominoes and clocks: the union of two views of the cell cycle (1989) Science, 246, p. 614
• Ortega, F., Acerenza, L., Westerhoff, H.V., Mas, F., Cascante, M., Product dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascades (2002) Proc Natl Acad Sci USA, 99, p. 1170
• Ortega, F., Garces, J.L., Mas, F., Kholodenko, B.N., Cascante, M., Bistability from double phosphorylation in signal transduction. Kinetic and structural requirements (2006) FEBS J., 273, p. 3915
• Ossareh, H.R., Ventura, A.C., Merajver, S.D., Del Vecchio, D., Long signaling cascades tend to attenuate retroactivity (2011) Biophys J, 100 (7), p. 1617
• Qiao, L., Nachbar, R.B., Kevrekidis, I.G., Shvartsman, S.Y., Bistability and oscillations in the huang-ferrell model of mapk signaling (2007) PLoS Comput Biol, 3 (9), p. 1819
• Snoussi, E., Thomas, R., Logical identification of all steady states: the concept of feedback loop characterisitic states (1993) Bull Math Biol, 55 (5), p. 973
• Thalhauser, C., Komarova, N., Signal response sensitivity in the yeast mitogen-activated protein kinase cascade (2010) PLoS One, 5 (7). , doi: 10. 1371/journal. pone. 0011568
• Thattai, M., van Oudenaarden, A., At- tenuation of noise in ultrasensitive signaling cascades (2002) Biophys J, 82, p. 2943
• Thomas, R., D'Ari, R., (1990) Biological Feedback, , Boca Raton: CRC Press
• Ventura, A.C., Sepulchre, J.A., Merajver, S.D., A hidden feedback in signaling cascades is revealed (2008) PLoS Comput Biol, 4 (3), pp. e1000041
• Ventura, A., Jackson, T., Merajver, S., On the role of cell signaling models in cancer research (2009) Cancer Res., 69, p. 400
• Ventura, A.C., Jiang, P., van Wassenhove, L., Del Vecchio, D., Merajver, S.D., Ninfa, A.J., Signaling properties of a covalent modification cycle are altered by a downstream target (2010) Proc Natl Acad Sci USA, 107 (22), pp. 10032-10037
• Wagner, E., Nebreda, A., Signal integration by jnk and p38 mapk pathways in cancer development (2009) Nat Rev Cancer, 9, p. 537
• Wynn, M.L., Ventura, A.C., Sepulchre, J.A., Garcia, H.J., Merajver, S.D., Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity (2011) BMC Syst Biol, 5, p. 156
• Zumsande, M., Gross, T., Bifurcations and chaos in the mapk signaling cascade (2010) J Theor Biol, 265, p. 481

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------