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antineoplastic agent
59
"Selective hemangioma cell dysfunction and apoptosis triggered by in vitro treatment with imiquimod"
(2018) Rocco, R.;Alegre, N.;Pozner, R. (
...
)Gazzaniga, S. Toxicology Letters. 288:82-88
"A Minimalist Approach to the Design of Complexity-Enriched Bioactive Small Molecules: Discovery of Phenanthrenoid Mimics as Antiproliferative Agents"
(2018) Alonso, F.;Quezada, M.J.;Gola, G.F. (
...
)Ramírez, J.A. ChemMedChem. 13(16):1732-1740
"Histamine H4 receptor as a novel therapeutic target for the treatment of Leydig-cell tumours in prepubertal boys"
(2018) Abiuso, A.M.B.;Varela, M.L.;Haro Durand, L. (
...
)Mondillo, C. European Journal of Cancer. 91:125-135
"Synthesis, antiviral and cytotoxic activity of novel terpenyl hybrid molecules prepared by click chemistry"
(2018) Pertino, M.W.; Petrera, E.; Edith Alché, L.; Schmeda-Hirschmann, G. Molecules. 23(6)
"Synthesis and cytotoxicity evaluation of A-ring derivatives of cycloartanone"
(2017) Zambrano, E.E.;Casas, A.G.;Di Venosa, G.M. (
...
)Palermo, J.A. Phytochemistry Letters. 21:200-205
"Phytochemical Study of the Genus Salpichroa (Solanaceae), Chemotaxonomic Considerations, and Biological Evaluation in Prostate and Breast Cancer Cells"
(2017) Basso, A.V.;Leiva González, S.;Barboza, G.E. (
...
)Nicotra, V.E. Chemistry and Biodiversity. 14(8)
"Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl D-ribofuranosides"
(2017) Avanzo, R.E.; Padrón, J.M.; D'Accorso, N.B.; Fascio, M.L. Bioorganic and Medicinal Chemistry Letters. 27(16):3674-3677
"Synthesis and in vitro antiproliferative activities of (5-aryl-1,2,4-oxadiazole-3-yl) methyl D-ribofuranosides"
(2017) Avanzo, R.E.; Padrón, J.M.; D'Accorso, N.B.; Fascio, M.L. Bioorganic and Medicinal Chemistry Letters. 27(16):3674-3677
"Photoactivation of Anticancer Ru Complexes in Deep Tissue: How Deep Can We Go?"
(2017) Sun, W.;Thiramanas, R.;Slep, L.D. (
...
)Wu, S. Chemistry - A European Journal. 23(45):10832-10837
"Minimally invasive electrochemotherapy procedure for treating nasal duct tumors in dogs using a single needle electrode"
(2017) Maglietti, F.;Tellado, M.;Olaiz, N. (
...
)Marshall, G. Radiology and Oncology. 51(4):422-430
"Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model"
(2017) Marostica, L.L.;de Barros, A.L.B.;Oliveira, J. (
...
)Simões, C.M.O. Toxicology and Applied Pharmacology. 329:272-281
"Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties"
(2015) Fascio, M.L.; Errea, M.I.; D'Accorso, N.B. European Journal of Medicinal Chemistry. 90:666-683
"Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties"
(2015) Fascio, M.L.; Errea, M.I.; D'Accorso, N.B. European Journal of Medicinal Chemistry. 90:666-683
"In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B"
(2015) Silva, I.T.;Carvalho, A.;Lang, K.L. (
...
)Ludwig, S. PLoS ONE. 10(2)
"Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549"
(2015) Marostica, L.L.;Silva, I.T.;Kratz, J.M. (
...
)Simões, C.M.O. Chemical Research in Toxicology. 28(10):1949-1960
"Low doses of CPS49 and flavopiridol combination as potential treatment for advanced prostate cancer"
(2015) Zalazar, F.;De Luca, P.;Gardner, K. (
...
)De Siervi, A. Current Pharmaceutical Biotechnology. 16(6):553-563
"Low doses of CPS49 and flavopiridol combination as potential treatment for advanced prostate cancer"
(2015) Zalazar, F.;De Luca, P.;Gardner, K. (
...
)De Siervi, A. Current Pharmaceutical Biotechnology. 16(6):553-563
"Human MageB2 protein expression enhances E2F transcriptional activity, cell proliferation, and resistance to ribotoxic stress"
(2015) Peche, L.Y.;Ladelfa, M.F.;Toledo, M.F. (
...
)Monte, M. Journal of Biological Chemistry. 290(49):29652-29662
"Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties"
(2015) Fascio, M.L.; Errea, M.I.; D'Accorso, N.B. European journal of medicinal chemistry. 90:666-683
"Arsenic trioxide alters the differentiation of mouse embryonic stem cell into cardiomyocytes"
(2015) Rebuzzini, P.;Cebral, E.;Fassina, L. (
...
)Garagna, S. Scientific Reports. 5
"The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy"
(2014) Orqueda, A.J.;Dansey, M.V.;Español, A. (
...
)Pecci, A. Biochemical Pharmacology. 89(4):526-535
"QSAR on antiproliferative naphthoquinones based on a conformation- independent approach"
(2014) Duchowicz, P.R.;Bennardi, D.O.;Bacelo, D.E. (
...
)Misico, R.I. European Journal of Medicinal Chemistry. 77:176-184
"QSAR on antiproliferative naphthoquinones based on a conformation- independent approach"
(2014) Duchowicz, P.R.;Bennardi, D.O.;Bacelo, D.E. (
...
)Misico, R.I. European Journal of Medicinal Chemistry. 77:176-184
"Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia"
(2014) Rocha-Viegas, L.;Villa, R.;Gutierrez, A. (
...
)Croce, L.D. Molecular and Cellular Biology. 34(19):3765-3775
"Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines"
(2014) Cardama, G.A.;Comin, M.J.;Hornos, L. (
...
)Menna, P.L. Anti-Cancer Agents in Medicinal Chemistry. 14(6):840-851
"Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines"
(2014) Cardama, G.A.;Comin, M.J.;Hornos, L. (
...
)Menna, P.L. Anti-Cancer Agents in Medicinal Chemistry. 14(6):840-851
"Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases"
(2014) Wan, X.;Corn, P.G.;Yang, J. (
...
)Navone, N.M. Science Translational Medicine. 6(252)
"Differential effect of heterocyclic d-ribofuranoside derivatives on human prostate cancer cell viability and cell cycle progression"
(2014) Gueron, G.;Avanzo, R.E.;Schuster, F. (
...
)D'Accorso, N.B. Biomedicine and Pharmacotherapy. 68(7):847-854
"Differential effect of heterocyclic d-ribofuranoside derivatives on human prostate cancer cell viability and cell cycle progression"
(2014) Gueron, G.;Avanzo, R.E.;Schuster, F. (
...
)D'Accorso, N.B. Biomedicine and Pharmacotherapy. 68(7):847-854
"Agarofuran sesquiterpenes from Schaefferia argentinensis"
(2013) García, M.E.;Motrich, R.D.;Caputto, B.L. (
...
)Nicotra, V.E. Phytochemistry. 94:260-267
"Vascular galectins: Regulators of tumor progression and targets for cancer therapy"
(2013) Thijssen, V.L.; Rabinovich, G.A.; Griffioen, A.W. Cytokine and Growth Factor Reviews. 24(6):547-558
"Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas"
(2013) Curic, S.;Wu, Y.;Shan, B. (
...
)Renner, U. Journal of Neuro-Oncology. 113(3):385-396
"β-Lapachone analogs with enhanced antiproliferative activity"
(2012) Ríos-Luci, C.;Bonifazi, E.L.;León, L.G. (
...
)Padrón, J.M. European Journal of Medicinal Chemistry. 53:264-274
"1,2,4-Triazole d-ribose derivatives: Design, synthesis and antitumoral evaluation"
(2012) Avanzo, R.E.;Anesini, C.;Fascio, M.L. (
...
)D'Accorso, N.B. European Journal of Medicinal Chemistry. 47(1):104-110
"Key questions in metastasis: New insights in molecular pathways and therapeutic implications"
(2011) Gueron, G.; de Siervi, A.; Vazquez, E. Current Pharmaceutical Biotechnology. 12(11):1867-1880
"FKBP51 and FKBP52 in signaling and disease"
(2011) Storer, C.L.;Dickey, C.A.;Galigniana, M.D. (
...
)Cox, M.B. Trends in Endocrinology and Metabolism. 22(12):481-490
"Cytotoxic terpenoids from Nardophyllum bryoides"
(2010) Sánchez, M.;Mazzuca, M.;Veloso, M.J. (
...
)Palermo, J.A. Phytochemistry. 71(11-12):1395-1399
"Cytotoxic terpenoids from Nardophyllum bryoides"
(2010) Sánchez, M.;Mazzuca, M.;Veloso, M.J. (
...
)Palermo, J.A. Phytochemistry. 71(11-12):1395-1399
"Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa"
(2010) De Almeida, M.T.R.; Ríos-Luci, C.; Padrón, J.M.; Palermo, J.A. Phytochemistry. 71(14-15):1741-1748
"Study of benzo[a]phenazine 7,12-dioxide as selective hypoxic cytotoxin-scaffold. Identification of aerobic-antitumoral activity through DNA fragmentation"
(2010) Lavaggi, M.L.;Cabrera, M.;Aravena, M.d.l.A. (
...
)Cerecetto, H. Bioorganic and Medicinal Chemistry. 18(12):4433-4440
"Endogenous and exogenous porphyrins as photosensitizers in the Hep-2 human carcinoma cell line"
(2009) Alvarez, M.G.;Milanesio, M.;Rivarola, V. (
...
)Fukuda, H. Cellular and Molecular Biology. 55(2):8-14
"Antiproliferative, cytotoxic and hemolytic activities of a triterpene glycoside from Psolus patagonicus and its desulfated analog"
(2009) Careaga, V.P.;Bueno, C.;Muniain, C. (
...
)Maier, M.S. Chemotherapy. 55(1):60-68
"Invasive giant prolactinoma with loss of therapeutic response to cabergoline: Expression of angiogenic markers"
(2009) Mallea-Gil, M.S.;Cristina, C.;Perez-Millan, M.I. (
...
)Becu-Villalobos, D. Endocrine Pathology. 20(1):35-40
"Nucleoside synthesis using a novel macroporous grafted polyethylene as biocatalyst support"
(2008) Trelles, J.A.;Bentancor, L.;Grasselli, M. (
...
)Iribarren, A.M. Journal of Molecular Catalysis B: Enzymatic. 52-53(1-4):189-193
"Nucleoside phosphorylases"
(2006) Lewkowicz, E.S.; Iribarren, A.M. Current Organic Chemistry. 10(11):1197-1215
"Induction of cell differentiation in human leukemia U-937 cells by 5-oxygenated-6,7-methylenedioxycoumarins from Pterocaulon polystachyum"
(2004) Riveiro, M.E.;Shayo, C.;Monczor, F. (
...
)Davio, C. Cancer Letters. 210(2):179-188
"New progresses in the enantioselective synthesis and biological properties of carbocyclic nucleosides."
(2003) Rodríguez, J.B.; Comin, M.J. Mini reviews in medicinal chemistry. 3(2):95-114
"p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells"
(2002) Martinez, L.A.;Yang, J.;Vazquez, E.S. (
...
)Navone, N.M. Carcinogenesis. 23(8):1289-1296
"Eruptive lesions in a patient with bone marrow transplantation"
(2001) Marini, M.;Saponaro, A.;Remorino, L. (
...
)Magariños, G. International Journal of Dermatology. 40(2):133-135
"Preparation and cytotoxicity toward cancer cells of mono(arylimino) derivatives of β-lapachone"
(2001) Di Chenna, P.H.;Benedetti-Doctorovich, V.;Baggio, R.F. (
...
)Burton, G. Journal of Medicinal Chemistry. 44(15):2486-2489
"On the promoting action of tamoxifen in a model of hepatocarcinogenesis induced by p-dimethylaminoazobenzene in CF1 mice"
(2001) Caballero, F.;Gerez, E.;Oliveri, L. (
...
)Vazquez, E. International Journal of Biochemistry and Cell Biology. 33(7):681-690
"Paesslerins A and B: Novel Tricyclic Sesquiterpenoids from the Soft Coral Alcyonium Paessleri"
(2001) Rodríguez Brasco, M.F.; Seldes, A.M.; Palermo, J.A. Organic Letters. 3(10):1415-1417
"Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters"
(2000) Palermo, J.A.; Brasco, M.F.R.; Spagnuolo, C.; Seldes, A.M. Journal of Organic Chemistry. 65(15):4482-4486
"Reactivity of monoclonal antibody FC-2.15 against drug resistant breast cancer cells. Additive cytotoxicity of adriamycin and taxol with FC-2.15"
(1998) Ballaré, C.;Portela, P.;Schiaffi, J. (
...
)Mordoh, J. Breast Cancer Research and Treatment. 47(2):163-170
"Evaluation of the porphyrinogenic risk of antineoplastics"
(1997) Cochón, A.C.; Aldonatti, C.; San Martín De Viale, L.C.; De Calmanovici, R.W. Journal of Applied Toxicology. 17(3):171-177
"Synthetic oligonucleotides and their application in gene therapy "
(1995) Iribarren, A.M. Medicina. 55(3):263-266
"Recent developments in the control of Trypanosoma cruzi, the causative agent for Chagas' disease"
(1995) Rodriguez, J.B.; Gros, E.G. Current Medicinal Chemistry. 2(3):723-742
"Effect of sulfation on the biological activity of β-(1→3)-glucans from the tree fungus Cyttaria harioti Fischer"
(1989) Fernandez Cirelli, A.;Covian, J.A.;Ohno, N. (
...
)Yadomae, T. Carbohydrate Research. 190(2):329-337
"Effect of some antineoplasics on metabolic heme pathway"
(1988) Wainstok De Calmanovici, R.; San Martin De Viale, L.C. International Journal of Biochemistry. 20(9):1015-1020
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